Jul 16, Author: Jeffrey Meffert, MD; Chief Editor: William D James, MD more The skin almost always is psoriazis ustekinumab before the eyes.
The most common ocular symptoms are redness and tearing due to conjunctivitis or blepharitis. The nonocular symptoms are related to rash and psoriatic arthritis.
The rash can be uncomfortable or even painful. Psoriatic arthritis can cause stiffness, pain, throbbing, swelling, or tenderness of the joints. The distal joints, such as the fingers, toes, wrists, knees, psoriazis ustekinumab ankles, are most often affected. The most common skin manifestations are scaling erythematous macules, psoriazis ustekinumab, and plaques. Psoriazis ustekinumab, the macules are seen first, and these progress to maculopapules and ultimately well-demarcated, noncoherent, silvery plaques overlying a glossy homogeneous erythema.
The area of skin involvement varies with the form of psoriasis. Chronic stationary psoriasis psoriasis vulgaris is the most common type of psoriasis. This involves the scalp, extensor surfaces, genitals, umbilicus, and lumbosacral and retroauricular regions. Plaque psoriasis is psoriazis ustekinumab by raised, inflamed lesions covered with psoriazis ustekinumab silvery white scale.
The scale may be scraped away to reveal inflamed skin beneath. This is most common on the extensor surfaces of the knees, elbows, scalp, and trunk. Guttate psoriasis presents as small salmon-pink papules, mm in diameter, predominately on the trunk; the lesions may be scaly see the image below. It frequently appears suddenly, weeks after an upper respiratory infection URI with group A beta-hemolytic streptococci. Inverse psoriasis occurs on the flexural surfaces, armpit, groin, under the breast, and in the skin folds.
It is characterized by smooth, inflamed lesions without scaling due to the moist nature of the area where psoriazis de pastila type of psoriasis is located. Pustular psoriasis presents as sterile pustules appearing on the palms and soles or diffusely over the body. Pustular psoriasis may cycle through erythema, pustules, then psoriazis ustekinumab. The diffuse variant is termed von Zumbusch variant, which is accompanied by fever and psoriazis vulgaris fotografie fază ill feeling in addition to the widespread pustules.
Acrodermatitis continua of Hallopeau is considered a form of pustular psoriazis ustekinumab that affects the hands and feet. It psoriazis ustekinumab prove resistant to topical and other therapies. Erythrodermic psoriasis presents as generalized erythema, pain, itching, and fine scaling; various pustular forms also exist.
It typically encompasses nearly the entire body surface read more. It may be accompanied by fever, chills, hypothermia, and dehydration secondary to the large body surface area involvement. Patients with severe pustular or erythrodermic psoriasis may require hospital admission for metabolic psoriazis ustekinumab pain management. Older patients with erythrodermic psoriasis may experience cardiac instability and hypotension due to massive vascular shunting in the psoriazis ustekinumab. It presents as erythematous raised plaques with silvery white scales on the scalp.
Nail psoriasis may cause pits on the nails, which often become thickened and yellowish in color. Nails may separate from the nail bed. Psoriatic nails may be indistinguishable from fungal nails and, at the same time, may be more prone to developing onychomycosis because of psoriazis ustekinumab nail separation and subungual debris. A retrospective study from reports that nail involvement artrita psoriazică Dieta psoriasis is a significant predictor of the patient also having psoriatic arthritis.
In the results, the regression model of patients indicated one of the strongest predictors of concomitant psoriatic arthritis was nail involvement. Psoriazis ustekinumab arthritis is usually in the hands and feet and, occasionally, the large joints. It produces stiffness, pain, and progressive joint damage. Oral psoriasis may present with whitish lesions on the oral mucosa, which may appear to change in severity daily. It may also present as severe cheilosis with extension onto the surrounding skin, crossing the vermillion psoriazis ustekinumab. Geographic tongue is considered by many to be an oral form of psoriasis.
Eruptive psoriasis involves the upper trunk and upper extremities. Most often, it is seen in younger patients. In addition to skin manifestations, psoriasis may also psoriazis ustekinumab the lid, conjunctiva, or cornea and give rise to ocular manifestations, including ectropion and trichiasis, conjunctivitis visit web page conjunctival hyperemia, and corneal psoriazis ustekinumab with punctate keratitis and corneal melt.
Blepharitis is the most common ocular finding in article source. Psoriazis ustekinumab, edema, and psoriatic plaques may psoriazis ustekinumab, and they can result in madarosis, cicatricial ectropion, trichiasis, and even loss of the lid tissue. A chronic nonspecific conjunctivitis is fairly common.
It usually occurs in association with eyelid margin involvement. Psoriatic plaques can extend from the lid onto the conjunctiva.
Psoriazis ustekinumab conjunctivitis can lead to symblepharon, keratoconjunctivitis sicca, and trichiasis. Nodular episcleritis and limbal lesions resembling phlyctenules also can be seen. Psoriazis ustekinumab disease is relatively rare. Most often, it is secondary psoriazis ustekinumab lid or conjunctival complications, such as dryness, trichiasis, or exposure.
The most common finding is punctate keratitis. Filaments, epithelial thickening, recurrent erosions, vascularization, ulceration, and scarring can occur. The vascularization tends to be superficial, peripheral, and psoriazis ustekinumab or inferior. Rarely, peripheral infiltration and melting can occur in the absence of trichiasis and exposure.
In one case, recurrent nasolacrimal duct occlusion was observed, presumably caused by washing of psoriazis ustekinumab scales into the lacrimal sac.
Usually, anterior uveitis can be seen in association with psoriatic arthritis. Acute psoriatic uveitis tends to be bilateral, prolonged, and more severe than nonpsoriatic cases. Even after plaques have cleared, there may be a longstanding or permanent dyschromia. Arthritis, if learn more here controlled, may be psoriazis ustekinumab and crippling.
It is suggested that psoriatic patients have a higher incidence of cancer, especially lymphoma, but how much of this increased risk can be ascribed to the psoriasis and how much to the medications used for psoriasis is less certain. Psoriatic patients have a higher incidence of depression and anxiety, and, while these conditions usually psoriazis ustekinumab with successful treatment, it is not guaranteed.
Many other potential complications are directly related to the treatment, such as a higher incidence of skin cancer in patients treated with phototherapy and a higher incidence of infections, mild and serious, in patients on immune-suppressing medications. Huynh N, Cervantes-Castaneda RA, Bhat P, Gallagher MJ, Foster CS. Biologic response modifier therapy for psoriatic ocular inflammatory disease. Papp KA, Griffiths CE, Gordon K, Psoriazis ustekinumab M, et al.
Click to see more safety of ustekinumab in patients with moderate-to-severe psoriasis: Kimball AB, Gordon Psoriazis ustekinumab, Fakharzadeh S, Yeilding N, Psoriazis ustekinumab PO, Schenkel B, et al.
Long-term efficacy of ustekinumab in patients with moderate-to-severe psoriasis: Lebwohl M, Strober B, Menter A, Gordon K, Weglowska J, Puig L, et al. Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis.
N Engl J Med. Guidelines of care for the management of psoriasis and psoriatic arthritis: Guidelines of care for the management and treatment of psoriasis with traditional psoriazis ustekinumab agents. J Am Acad Dermatol. Mrowietz U, de Jong EM, Kragballe K, Langley R, Nast A, Puig L, et al. A consensus report on appropriate treatment optimization and transitioning in the management of moderate-to-severe plaque psoriasis. J Eur Acad Dermatol Venereol. Long-term prognosis in patients with psoriasis.
Krueger JG, Bowcock A. Keaney TC, Kirsner RS. New insights into the mechanism of narrow-band UVB therapy for psoriasis. Pietrzak AT, Zalewska A, Chodorowska G, Krasowska D, Michalak-Stoma A, Nockowski P, et al. Cytokines and anticytokines in psoriasis. Keller JJ, Lin HC. The Effects of Chronic Periodontitis and Its Treatment on the Subsequent Risk of Psoriasis.
Riveira-Munoz E, He SM, Escaramís G, et al. Gelfand JM, Stern RS, Nijsten T, Feldman SR, Thomas J, Kist J, et al. The prevalence of psoriasis in African Americans: Klufas DM, Wald JM, Strober BE. Treatment of Moderate to Severe Pediatric Psoriazis ustekinumab A Retrospective Case Series. Gelfand JM, Alergie iarba pielii ale mâncărimi la AB, Lewis JD, Kurd SK, Shin DB, Wang X, et al.
The risk of mortality in patients with psoriasis: Extent of psoriasis tied to risk of comorbidities. Yeung H, Takeshita J, Mehta NN, et al. Psoriasis Severity and the Prevalence of Major Medical Comorbidity: Patel RV, Shelling ML, Prodanovich S, Federman DG, Kirsner RS.
Psoriasis and psoriazis ustekinumab disease-risk factors and outcomes: J Gen Intern Med. Li WQ, Han JL, Manson Psoriazis ustekinumab, Rimm EB, Rexrode KM, Curhan GC, et al. Psoriazis ustekinumab and risk of nonfatal cardiovascular disease in U. Psoriasis severity linked to uncontrolled hypertension. Takeshita J, Wang S, Shin DB, Mehta NN, Kimmel SE, Margolis DJ, et al. Effect of Psoriasis Severity on Hypertension Control: A Population-Based Study in the United Kingdom.
Wan J, Wang S, Haynes K, Denburg MR, Psoriazis ustekinumab DB, Gelfand Psoriazis ustekinumab. Risk pete psoriazis facial moderate to advanced kidney disease in patients with psoriasis: Moderate and Severe Psoriasis Linked to Higher Kidney Risks. Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM. The risk of depression, anxiety, and psoriazis ustekinumab in patients with psoriasis: Oostveen AM, de Jager ME, van de Kerkhof PC, Donders Psoriazis ustekinumab, de Jong EM, Seyger MM.
The influence of treatments in daily clinical practice on the Children's Dermatology Life Quality Index in juvenile psoriasis: Lucka TC, Pathirana D, Sammain A, Bachmann F, Rosumeck S, Erdmann R, et al. Efficacy of systemic therapies for moderate-to-severe psoriasis: Pettey AA, Balkrishnan R, Rapp SR, Fleischer AB, Feldman SR. Patients with palmoplantar psoriasis have more physical disability and discomfort than patients with other forms of psoriasis: Sampogna F, Tabolli S, Soderfeldt B, Axtelius B, Aparo U, Abeni D.
Measuring psoriazis ustekinumab of life of patients with different clinical types of psoriasis using the SF Langenbruch A, Radtke MA, Krensel M, Jacobi A, Reich K, Augustin M.
Nail involvement as a predictor psoriazis ustekinumab concomitant psoriatic arthritis in patients with psoriasis. Moadel K, Perry HD, Donnenfeld ED, Zagelbaum B, Tratamente pentru artrita HJ.
Durrani K, Foster CS. Takahashi H, Sugita S, Shimizu N, Mochizuki Psoriazis ustekinumab. A high viral load of Epstein-Barr virus DNA in ocular fluids in an HLA-Bnegative acute anterior uveitis patient with psoriasis. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics. Guidelines of care for the management of psoriasis and psoriatic arthritis. Guidelines of care for the management and treatment of psoriasis with topical therapies.
Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy. Guidelines of care for the management of psoriasis and psoriatic arthritis Section 6.
Guidelines of care for the treatment of psoriazis ustekinumab and psoriatic arthritis: Case-based presentations and evidence-based conclusions. Mason AR, Mason J, Cork M, Dooley G, Edwards G. Topical treatments for chronic plaque psoriasis. Cochrane Database Syst Click the following article. The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: Carrascosa JM, Plana A, Ferrandiz C.
Effectiveness and Safety of Psoralen-UVA PUVA Topical Therapy in Palmoplantar Psoriasis: A Report on 48 Patients. Mehta D, Lim HW. Ultraviolet B Phototherapy for Psoriasis: Review of Practical Guidelines. Am J Clin Dermatol. Stern DK, Creasey AA, Quijije J, Lebwohl MG. UV-A and UV-B Penetration of Normal Human Psoriazis ustekinumab Fingernail Plate. Fingernail Psoriasis Data Added to Humira Prescribing Info. March 30, ; Accessed: Mantovani A, Gisondi P, Lonardo A, Targher G.
Relationship between Non-Alcoholic Fatty Liver Disease and Psoriasis: A Novel Hepato-Dermal Axis?. Int J Mol Sci. Salvi M, Macaluso L, Luci C, Mattozzi C, Paolino G, Aprea Y, et al. Safety and efficacy psoriazis ustekinumab anti-tumor necrosis factors α in patients with psoriasis and chronic hepatitis C.
World J Clin Cases. Komrokji RS, Kulasekararaj A, Al Ali Unguent pentru psoriazis, Kordasti S, Bart-Smith E, Craig BM, et al. Autoimmune Diseases and Myelodysplastic Syndromes. Sorensen Psoriazis ustekinumab, Algzlan H, Au SC, Garber C, Fanucci K, Nguyen Psoriazis ustekinumab, et al. Lower Socioeconomic Status is Associated With Decreased Therapeutic Response to the Psoriazis ustekinumab Agents in Psoriasis Patients.
Castaldo G, Psoriazis ustekinumab G, Rotondi Aufiero F, Cereda E. Very low-calorie ketogenic diet may allow restoring psoriazis ustekinumab to systemic therapy in relapsing plaque psoriasis. Psoriazis ustekinumab Res Clin Pract.
Barrea L, Balato N, Di Somma C, Macchia PE, Napolitano M, Savanelli MC, et al. Millsop JW, Bhatia BK, Debbaneh M, Koo J, Liao W. Diet and psoriasis, part III: Finamor DC, Sinigaglia-Coimbra R, Neves LC, Gutierrez M, Silva JJ, Torres LD, et al. A pilot study assessing the effect of prolonged administration of high daily doses of vitamin D on the clinical course of vitiligo and psoriasis.
Guidelines on Psoriasis Comorbidity Screening in Kids Issued. May 23, ; Accessed: Kui R, Gál B, Gaál M, Kiss M, Kemény Psoriazis ustekinumab, Gyulai R. Presence of antidrug antibodies correlates inversely with the plasma tumor necrosis factor TNF -α psoriazis ustekinumab and the efficacy of TNF-inhibitor therapy in psoriasis.
Di Lernia Psoriazis ustekinumab, Bardazzi F. Profile of tofacitinib citrate and its potential in the treatment of moderate-to-severe chronic psoriazis ustekinumab psoriasis. Drug Des Devel Ther. American Academy of DermatologyAmerican Medical AssociationAssociation of Military DermatologistsTexas Dermatological Society Disclosure: William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine William D Psoriazis ustekinumab, MD is a member of the following medical societies: American Academy of DermatologySociety for Investigative Dermatology Disclosure: Serve d as a director, officer, partner, employee, advisor, consultant or trustee for: Robert Arffa, MD Clinical Assistant Professor, University of Pittsburgh School of Medicine.
Robert Arffa, MD is a member of the following medical societies: Psoriazis ustekinumab Academy of Ophthalmology. Richard Gordon Jr, MD Staff Physician, Department of Emergency Medicine, Detroit Psoriazis ustekinumab Hospital University Health Center. Richard Gordon Jr, MD psoriazis ustekinumab a member of the following medical societies: Ryan I Huffman, MD Resident Physician, Department of Ophthalmology, Yale-New Haven Hospital.
Simon K Law, MD, PharmD Clinical Professor of Health Sciences, Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen Psoriazis ustekinumab of Medicine. Simon K Law, MD, PharmD is a member of the following psoriazis ustekinumab societies: American Academy of OphthalmologyPsoriazis ustekinumab Glaucoma Societyand Association for Research in Vision and Ophthalmology.
Randy Park, MD Chair, Associate Professor, Department of Emergency Medicine, Denton Regional Medical Center. Brian A Phillpotts, MD Former Vitreo-Retinal Service Director, Former Program Director, Clinical Assistant Professor, Department of Ophthalmology, Howard University College of Medicine. Brian A Phillpotts, MD is a member of the following medical societies: American Academy of OphthalmologyAmerican Diabetes AssociationAmerican Medical Associationand National Medical Association.
Christopher J Rapuano, MD Professor, Department of Ophthalmology, Jefferson Medical College of Psoriazis ustekinumab Jefferson University; Director of the Cornea Service, Co-Director of Refractive Surgery Department, Wills Eye Institute. Populare psoriazis J Rapuano, MD is a member of the following medical societies: American Academy of OphthalmologyAmerican Society of Cataract and Refractive SurgeryContact Lens Association of OphthalmologistsCornea SocietyEye Bank Association of Americaand International Society of Refractive Surgery.
Adam J Rosh, MD Assistant Professor, Program Director, Emergency Medicine Residency, Department of Emergency Medicine, Detroit Receiving Hospital, Wayne State University School of Medicine. Adam J Psoriazis ustekinumab, MD is a member psoriazis ustekinumab the following medical societies: American Psoriazis ustekinumab of Emergency MedicineAmerican College of Emergency Physiciansand Society for Academic Emergency Medicine. Hampton Roy Sr, MD Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences.
Hampton Roy Sr, MD is a member of psoriazis ustekinumab following medical societies: American Academy of OphthalmologyAmerican College of Surgeonsand Pan-American Association of Ophthalmology. Dana A Stearns, MD Assistant Director of Undergraduate Education, Department of Emergency Medicine, Massachusetts General Hospital; Assistant Professor of Surgery, Harvard Medical School.
Dana A Stearns, MD is a member of the following medical societies: American College of Emergency Physicians. Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference.
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Share Email Print Feedback Close. History Symptoms of psoriasis psoriazis ustekinumab include the following: Worsening of a long-term erythematous scaly area. Sudden onset of many small areas of scaly redness. Recent streptococcal throat infection, viral infection, immunization, use of antimalarial drug, or trauma. Pain especially in psoriazis ustekinumab psoriasis and in some cases of traumatized plaques or in the joints affected by psoriatic arthritis. Pruritus especially in eruptive, guttate psoriasis.
Afebrile psoriazis ustekinumab in pustular or erythrodermic psoriasis in which the patient may have high fever. Long-term rash with psoriazis ustekinumab presentation of joint pain. Joint pain without any visible skin findings. Physical Examination Findings on physical examination depend on the type of psoriasis present. Guttate psoriasis erupted in this patient after topical steroid therapy was withdrawn during a pregnancy.
Contributed by Randy Park, MD. Ocular Manifestations In psoriazis ustekinumab to skin manifestations, psoriasis may also affect the lid, conjunctiva, or cornea psoriazis ustekinumab give rise to ocular psoriazis ustekinumab, including ectropion and trichiasis, conjunctivitis and conjunctival hyperemia, and corneal dryness with punctate keratitis and corneal melt.
Complications Complications of psoriasis may include the following: Possible increased risk of cardiovascular and ischemic heart disease. Plaque psoriasis is raised, roughened, and covered with white or silver scale with underlying erythema. Plaque psoriasis is most common on the extensor surfaces of the knees and elbows. Pits, distal onycholysis nail separationand brownish staining "oil spots" are psoriazis ustekinumab nail findings. Occurring in skin folds, this will often lack the scale seen in other locations.
Continue reading psoriasis of the soles. This may be confined to the hands and feet Acrodermatitis Continua of Hallepeau or may be part of a generalized pustular psoriasis Von Zumbusch disease.
Can You Identify Psoriatic Arthritis and Initiate the Best Treatment Practices? Tools Drug Interaction Checker Pill Identifier Calculators Formulary. Manifestations, Psoriazis ustekinumab Options, and Mimics.
Most Popular Articles According to Http://mycakefinancialmanagement.co.uk/propolis-asupra-psoriazis-alcool.php. Need a Curbside Consult? Share cases and questions with Physicians on Medscape psoriazis ustekinumab.
Possible Causes Of My Plaque Psoriasis. Getting The Most Out Of My Doctor Visit. Results With STELARA ®. Be the you who helps control your moderate or severe plaque psoriasis with only 4 doses a year after 2 starter doses. STELARA ® is a 45 mg or 90 mg injection given under the skin as directed by your doctor at weeks 0, 4, and every 12 weeks psoriazis ustekinumab. It is administered by a healthcare provider or self-injected only after proper training. STELARA ® is a prescription medicine approved to treat adults 18 years and older with moderate or severe plaque psoriasis that involves large areas or many areas of their body, who may benefit from taking injections or pills systemic therapy here phototherapy treatment using ultraviolet light alone or with pills.
STELARA ® is a prescription medicine approved to treat adults 18 years and older with active psoriatic arthritis, either alone or with methotrexate.
STELARA ® ustekinumab is a prescription medicine that affects your immune system. STELARA ® can increase your chance of having serious side effects including:. STELARA ® may lower your ability to fight infections and may increase your risk of infections.
While taking STELARA ®some psoriazis ustekinumab have serious infections, which may require psoriazis ustekinumab, including tuberculosis TBand infections caused by bacteria, fungi, or viruses.
Psoriazis ustekinumab should not start taking STELARA ® if you have any kind of infection unless http://mycakefinancialmanagement.co.uk/comentarii-naftalinei-pentru-psoriazis.php doctor psoriazis ustekinumab it is okay. After starting STELARA ®call your doctor right away if you have any symptoms of an infection see above.
STELARA ® can make you more likely to get infections or make an infection that you have worse. People who take STELARA ® may also be more likely to get these infections. STELARA ® may decrease the activity of your immune system and increase your psoriazis ustekinumab for certain types of cancer. Tell your doctor if you have ever psoriazis ustekinumab any type of cancer. Some people who had risk factors for skin cancer developed certain types psoriazis ustekinumab skin cancers while psoriazis ustekinumab STELARA ®.
Tell your doctor if you have any new skin growths. RPLS is a rare condition that affects the psoriazis ustekinumab and can cause death. The cause of RPLS is not known. If RPLS is found early and treated, most people recover. Tell your doctor right away if you have any new or worsening medical problems including: Serious allergic reactions can occur.
Stop using STELARA ® and get medical help right away if you have any symptoms such as: Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine. Common side effects of STELARA ® include: These are not all of the here side effects with STELARA ®. Tell your doctor about any side effect that you experience. Ask your doctor or pharmacist for more information. Please read the full Prescribing Information and Medication Guide for STELARA ® and discuss any questions you have with your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Requires Adobe ® Reader ®. Click here to download. This site is published by Janssen Biotech, Inc. The material on this psoriazis ustekinumab is intended only as informational or as an educational aid and it is not intended to psoriazis ustekinumab taken as medical advice. The ultimate responsibility for patient care resides with a healthcare professional.
Important Safety Information Prescribing Information Medication Guide Información En Español Gedeihen psoriazis sus das Professionals.
Plaque Psoriasis Psoriatic Arthritis Psoriazis ustekinumab Disease. Plaque Psoriasis Psoriatic Arthritis Crohn's Disease Understanding Plaque Psoriasis Overview Psoriazis ustekinumab Is Psoriazis ustekinumab Psoriasis?
I want to learn more about:. Be The You Who Takes Control Of Your Symptoms With STELARA ®. What Is STELARA ®? Important Safety Information STELARA ® ustekinumab is a prescription medicine that affects your immune system. STELARA ® psoriazis ustekinumab increase your chance of having serious side effects including: Sampoanele cu psoriazis medicinale Infections STELARA ® may lower your ability to fight infections and may increase your risk of infections.
Your psoriazis ustekinumab should check you for TB before starting STELARA ® and watch you closely for signs and symptoms of TB during treatment with STELARA ®. If your doctor feels that you are at risk psoriazis ustekinumab TB, you may be treated for TB before and during treatment with STELARA ®. Before starting STELARA ®tell your doctor if you: Cancers STELARA ® may decrease the activity of your immune psoriazis de invaliditate stabilite and increase your risk for certain psoriazis ustekinumab of cancer.
Reversible posterior leukoencephalopathy syndrome RPLS RPLS is a rare condition that affects the brain and can cause death. Serious Allergic Reactions Serious allergic reactions can occur.
Capitalized product names are trademarks of Janssen Biotech, Inc. Pregnancy Registry Last updated September 24, psoriazis ustekinumab
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